Magnesium and Chelation – How to detoxify heavy metals, aluminum and endocrine disruptors from the body.
Magnesium deficiency is an obstacle to the chelation of toxins. Magnesium Disodium versions of EDTA (Magnesium Disodium EDTA (C10H12MgN2Na2O8)), the most widely recognized chelation agent for heavy metals and certain minerals, can be easily found in medical literature and needs no introduction here (1). This EDTA stands as proof of magnesium’s role in the synergy of chelation in the human body. How acids and metals or certain mineral salts react outside of the body, by mixing industrially produced acids to specific metals to produce combined forms, should not be confused with the “seemingly identical” process mirrored within the living human body.
In the living body, enzymes play a key role in these interactions. Magnesium is involved in all of these interactions through the enzymes’ own dependence on magnesium for a more perfect transformation, catalyzation, chelation or conjugation. Magnesium is an essential factor for enzyme efficiency. Magnesium is also a natural calcium channel blocker, reducing the cell’s rigidity.
Many supplements which have been made outside the body such as magnesium malate, magnesium citrate, magnesium aspartate, magnesium glycinate, magnesium threonate, etc., differ from the R-form, natural and mirror molecule within the living body. The body creates these forms from the base magnesium chloride molecule by acidification processes combined with lipid molecules (fats) to create what it needs internally. This does not mean that these supplements do not have value as they can be helpful in certain situations. However, once the transdermal route for magnesium chloride is understood fully in the future, as it was in the past through the Roman and Greek thallaso, bath and thermal culture of Antiquity, we will realize that the skin is the ideal, yet overlooked, place for these transformations into the various magnesium combinations the body needs.
Malic acid is a well known chelation agent of aluminum in the body (2). Aluminum is one of the most pervasive toxins in the environment and in the body. Malic acid is not only found in apples but it is also found at the cellular level and is part of the ATP cycle, known as the malate-aspartate shuttle. Magnesium combines with malic acid to form magnesium malate, which becomes a fierce detoxifier of aluminum in the body. Many cosmetics use malic acid as it falls under the category of AHA (alpha-hydroxy acids), beneficial catalysts in the propagation of skin cells and tissue regeneration. The skin, as a barrier, has a natural acidity. The acids in the skin act not only as a protective agent, but as in the process of fermentation, they help create a living flora on the skin. When applied, magnesium chloride brine, the base form of magnesium from the sea or from crystallized sea strata within the Earth, penetrates into the skin and combines with these acids in the first layer, then fats in the next layers, to be better assimilated and used by the body.
Magnesium is also a well known antagonist to the fixation of aluminum (along with calcium), if optimal levels of magnesium are maintained. Nutrient-dense nutrition alongside the transdermal application practiced by our ancestors, as mentioned above, is key here. In France, doctors still prescribe bathing in certain mineral-rich waters found throughout France for many different conditions from rheumatism, to fatigue, stress, and lung disorders. Many in America have forgotten these traditions.
Magnesium is also an antagonist to cadmium, lead, nickel, and beryllium absorption in the body (3)(4)(5). Increased magnesium intake facilitates the elimination of cadmium through urinary excretion (4). Magnesium along with a healthy metabolism is also antagonistic to lead absorption in the vital organs.
Why is purity so important for the chelation and removal of modern toxins, heavy metals, endocrine disruptors and the acid residues which cause aging ?
A naturally formed soft stone called bischofite, found in the crystalized Zechstein Sea deposits underneath the city of Veendam in Holland, contains the only form of pure magnesium chloride. 95% of magnesium oils, magnesium chloride, magnesium carbonate and the base form of magnesium used to create most supplements come from chemically treated, solvent treated magnesium deposits. These deposits must then be “upgraded”, the industry-wide term for this, to separate the “derivative magnesium” from potassium, heavy metals and other contaminants such as bromine (Dead Sea) or mercury (Salt Lake). This magnesium is stripped and sterilized to be the isolated substance MgCl. Whereas natural magnesium chloride, being pure in its natural state without contaminants, allows for a better uptake by magnesium dependent enzymes. These enzymes, in turn, create stronger bonds, more efficient conjugation and more efficient uptake, through their acidic conjugations, such as magnesium malate, to better remove aluminum and other toxins. One does not need a study to know that one can build better with the stones that nature intended.
Why are glass containers so important ?
If, instead of pouring pure, low-oxygen sealed, 1000 liter cubes of magnesium oil into glass bottles, one decided to pour this substance into thousands of user-end, soft, made for appearance, thin plastics we would effectively increase by 500% the level of exposure of the dry-oil substance to endocrine disruptors and micro-plastics. Endocrine disrupting chemicals (EDC) absorb quickly into the oil when one multiplies the surface area contact. Additional leeching would occur, during storage and usage, as the plastic degrades in contact with halogens, lighting and oxygen. This would not only reduce the initial quality of the substance but it would limit the magnesium’s capacity, through magnesium-dependent enzymes in the body, to remove these same endocrine disruptors from the body. “First, do no harm” is the first rule of medicine. However EDC’s found in the tissues can be removed and reduced through transpiration. Transpiration has been proven, in animal studies, to remove these chemicals in conjunction with adequate magnesium levels. These two components are also found in sweat samples. It is a simple logic that the less you contaminate yourself with EDC’s, especially for such an important mineral such as magnesium, the less effort (years) it will take to remove them.
Sources :
(1) https://pubchem.ncbi.nlm.nih.gov/compound/Magnesium-Disodium-EDTA
(2) Comparative effects of several chelating agents on the toxicity, distribution and excretion of aluminium.
Domingo JL1, Gómez M, Llobet JM, Corbella J.
(3) Correlations between magnesium and heavy metals in blood and sixteen tissues of rabbits.
Speich M1, Auget JL, Arnaud P.
(4) Contribution to interaction between magnesium and toxic metals: the effect of prolonged cadmium intoxication on magnesium metabolism in rabbits.
Soldatovi D., Matovi V., Vujanovi D., Stojanovi Z.
(5) Antagonism between cadmium and magnesium: a possible role of magnesium in therapy of cadmium intoxication.
Matovi V., Plamenac Bulat Z., Djuki-Cosi D., Soldatovi D.